Wednesday, 3 July 2013

Serotonin Syndrome Information

Serotonin syndrome is a life-threatening drug reaction that causes the body to have too much serotonin, a chemical produced by nerve cells. It is an iatrogenic (i.e. caused by medical treatment) toxidrome. Serotonin syndrome is caused by increased serotonin in the central nervous system. It is the result of overstimulation of 5-HT1A receptors in central grey nuclei and the medulla and, perhaps, of overstimulation of 5-HT2 receptors. Serotonin syndrome is not a spontaneous drug reaction, it is a consequence of excess serotonergic activity at central nervous system (CNS) and peripheral serotonin receptors. Serotonin syndrome can occur when you take certain combinations of prescription medications that affect serotonin levels in your body.

Signs and symptoms of serotonin syndrome range from restlessness and rapid heartbeat to muscle rigidity and seizures. Severe case often have agitated delirium as well as muscular rigidity and high muscular tension. Temperature may rise to above 41.1C (105.98F) in life-threatening cases. Other abnormalities include metabolic acidosis, rhabdomyolysis, seizures, renal failure, and disseminated intravascular coagulation. Risk factors for the development of serotonin syndrome are unclear, but some trends are becoming apparent as more cases appear in the literature. Peripheral vascular disease and atherosclerosis may lead to severe vasospasm and hypertension in the presence of elevated serotonin levels. Another risk factor relates to drug metabolism rate.
Slow metabolizers of SSRIs (approximately 7% of the population) may produce higher than normal levels of these antidepressants in the blood. Serotonin syndrome can be life threatening. The most important treatment is to discontinue the offending agent. Benzodiazepines, such as diazepam (Valium) or lorazepam (Ativan), can help control agitation, seizure-like movements and muscle stiffness. Moderate cases should have all thermal and cardiorespiratory abnormalities corrected and can benefit from serotonin antagonists (i.e. cyproheptadine). Esmolol (Brevibloc) or nitroprusside (Nitropress) drugs to reduce an increased heart rate or high blood pressure. If other treatments aren't working cyproheptadine (Periactin), a drug that blocks serotonin production.

Serotonin Syndrome Treatment Tips

1. Cyproheptadine (Periactin), a drug that blocks serotonin production.

2. Lorazepam and diazepam have been shown to be effective in treating serotonin syndrome.

3. Benzodiazepines, such as diazepam (Valium) or lorazepam (Ativan), can help control agitation.

4. Rigidity, seizures, and agitation are treated with benzodiazepines.

5. Esmolol or nitroprusside drugs to reduce an increased heart rate or high blood pressure.





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Tuesday, 2 July 2013

Culantro: Caribbean And West Indian Jewel of Culinary Herbs And It's Medicinal Applications

Culantro is a biennial herb grown throughout the Caribbean, the West Indies and Central America. While it is widely used as a food flavoring and seasoning herb for meat and many other foods in various Caribbean and West Indian countries, it is also known commonly for its medicinal qualities. It is also a key in Puerto Rican and Cuban cuisines .

Culantro is more penetrating in flavor than cilantro. On its spine-like leaves are tiny edges which make harvesting a unique and sometimes unpleasant experience. (1)

Culantro (Eryngium foetidum) and Cilantro (Coriandrum sativum) and what is commonly known as Coriander are not one and the same plant. But they are related and considered not too distant cousins. Culantro (broad leaf variety), is native to Latin America, the West Indies and the Caribbean. It is primarily distinguished from its cilantro and coriander cousins by its long, stiff and sharp serrated leaves which make harvesting sometimes very unpleasant.

In Vietnam and the rest of Asia, culantro is also known and is most popular in Thailand, Malaysia, and Singapore, where it is commonly used with or instead of cilantro for soups, noodle dishes, and curries. In recent times, because of the presence of increasingly large West Indian, Latin American, and Asian immigrant communities in metropolises of the US, Canada and the UK, there has been created a large market for culantro and large quantities are today exported from Puerto Rico, the Caribbean and Trinidad in the West Indies to these areas.

Nutrient Value and Composition

Culantro is rich in calcium, iron, carotene, and riboflavin. Fresh leaves are 86-88% moisture, 3.3% protein, 0.6% fat, 6.5% carbohydrate, 1.7% ash, 0.06% phosphorus, and 0.02% iron. They are also an excellent source of vitamin A (10,460 I.U./100 g), B2 (60 mg %), B1 (0.8 mg %), and C (150-200 mg %) (Bautista et al. 1988). It is this richness in it's medicinal properties which make culantro a choice herb for curative applications.

Typical Applications and Medicinal Uses

Among other things, the Vietnamese use it to wrap other foods, as one would wrap food in plantain leaves or cabbage leaves. At one time, candied culantro seeds were popular in eighteenth-century Britain as a tonic, a cough remedy, and an aphrodisiac.

Its medicinal value applications includes its use as a tea for flu, diabetes, constipation, vomiting, diarrhea and principally in Jamaica for colds. In the Caribbean and West Indian cuisine, its most popular uses is in chutney as an appetite stimulant. It is also used for its supposedly anti-convulsive properties, especially in children.

The leaves and roots are boiled and the water drunk for treating pneumonia, flu, diabetes, constipation, and malaria fever. The root can be chewed for cutting the poison from scorpion stings and in India the root is reportedly used to alleviate stomach pains. The leaves themselves can be eaten to stimulate appetite and are used in Jamaica and the West Indies for this purpose. The cilantro leaves can be used to prepare a variety salsas, gravies, barbecued foods and even appetizing drinks. (2)

Growing Culantro: It is a curious fact that in warmer climates, Zone 7 and above, the actual culantro plant can be reseeded and grown commercially. The typical manner in harvesting the leaves is to simply cut them off at the base as they appear. In zones 7 and below the climate is more appropriately seasonal for cilantro. However, many people buy the plant expecting it to bear leaves for an extended period, and they are disappointed to find that culantro it will not. The reason is true culantro, in heat, is working to expend it's energies to go to seed, coriander.

Leaves are actually herbs while seeds are spice, as a general rule, just as culantro, cilantro and coriander are two different animals. Adding to the apparent confusion of many persons is that culantro is known by so many, many names such as: Puerto Rican coriander, Black Benny, saw leaf herb, Mexican coriander, Saw tooth coriander, long coriander, Spiny coriander, Fitweed, and spiritweed. In Puerto Rico it is known as recao.

Culantro thrives under well-watered, shady conditions. It like moisture but does not do well soaked. It likes the sun but only partial sun. Because it prefers the shade or partial sun, its love of warm weather makes it a good substitute for the cool weather loving cilantro. Culantro is the answer for those who enjoy cilantro but live in a hot/warm climate and want fresh culantro all spring/summer and fall.

Culantro can be planted in pots or on the ground.If planted in the ground, this herb will continue to reproduce for an endless supply, into infinity almost. Culantro is relatively pest and disease free. It is rumored to be attractive to beneficial insects such as ladybugs, green lacewings, and to provide an excellent defense in the garden against aphids. (3)

To harvest, remove the oldest leaves all the way down to the base of the plant leaving the young new leaves to grow. The leaves can be chopped and used fresh or frozen to keep their flavor. Unlike cilantro, culantro doesn't bolt, it will produce tiny black seeds which when simply thrown in the ground will produce more abundant culantro.

Serving Suggestions:

In cooking it is used to flavor salsa, softrito, chutney, ceviche, sauces, rice, stews, and soups.

Make Mexican pico de gallo by combining chopped tomatoes, green chiles, onion, lime juice, and plenty of chopped cilantro. Season Cuban black beans and Puerto Rican pink beans with culantro. Add Vietnamese coriander at the last minute to Vietnamese soups and Malaysian noodle dishes.

Food Affinities Photo: Courtesy Wikipedia

Cilantro: (can be used interchangably with culantro). Avocado, beef, ceviche, chicken, chiles, ginger, lime, onion, pork, pumpkin seed, shrimp, tomato, turkey.

Culantro: Annatto, black beans, chiles, garlic, ginger, lemongrass, scallion, sesame oil, wild lime leaf.

Vietnamese coriander: Bean sprouts, celery, chicken, chiles, coconut milk, crab, seafood, shrimp paste.

Simple Recipe for Pico de Gallo

In Mexican cuisine, pico de gallo (Spanish for "rooster's beak"), is also called salsa fresca and is a fresh, uncooked condiment made from chopped tomato, onion, and sometimes chilis (typically jalapeos or serranos). Other ingredients may also be added, such as lemon or lime juice, fresh cilantro (coriander leaf), cucumber, radish or other fresh firm pulpy fruit such as mango.

Pico de gallo can be used in much the same way as other Mexican salsas, or Indian chutneys, but since it contains less liquid, it can also be used as a main ingredient in dishes such as tacos and fajitas. Simply chop all ingredients and mix together adding lemon or lime juice. Add hot sauce, salt and pepper to taste.

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Sources:

(1) /newcrop/proceedings1999/v4-506.html

(2) Bob Johnson,/?expert=Bob_G_Johnson

(3) Bob Johnson,/?expert=Bob_G_Johnson

Authored by Beverly Anne Sanchez, 2010





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Gestational Diabetes Test - What is it And How do I Prepare?

During even a low risk pregnancy, you'll find there are many different tests you'll experience, from the first pregnancy test through to regular urine tests, blood pressure tests, blood tests and a gestational diabetes test.

Gestational diabetes is a complication more common in women who have health or weight problems or are experiencing pregnancy at an older age. Even if you're not in the risk category for gestational diabetes you'll still probably be tested for it.

Before you begin to worry about such a scary sounding problem, just remember this - many women who get it have never had any type of diabetes before pregnancy and many of these women often find it disappears within a few weeks of baby's birth. The most important thing is diagnosing and treating it during pregnancy.

This article is written as a guide to Glucose Tolerance Tests, what to expect and how to prepare for them.

What is Gestational Diabetes?

Gestational Diabetes is a pregnancy induced problem with the insulin produced by your pancreas. The insulin plays in important role in processing the sugars you eat.

What are the risks of having untreated Gestational Diabetes?

Some of the basic problems associated with Gestational Diabetes include very large babies, which may lead to an early induction or caesarian.

The large amount of glucose that crosses through the placenta forces the baby's pancreas to work overtime. Baby's body will create extra energy which is then stored as fat. This can also lead to higher risk of obesity and diabetes in later life for the child.

Glucose problems can also have an adverse effect on baby's breathing at birth.

What does the Glucose drink taste and look like?

The Glucose drink doesn't taste bad - in fact it tastes almost exactly like lemonade. It's a clear liquid in a small bottle and is generally only about 500 ml.

What types of Glucose Tolerance Tests are there?

There are several types of tests, depending on where you live and your risk of having gestational diabetes.

The tests are known as Glucose Tolerance Tests (GTT) and involve drinking a sugary liquid after which you'll be tested to see how your body reacts to the liquid.

Preparing for your Test

It's important to prepare for the test correctly, so that you don't have a false positive or need to retake the test. The following are guidelines only and should be checked with your doctor before the test.

Don't eat or drink anything but water in the 12 hours before the test. (If you do, it may result in a false positive.)

Make sure you have at least an hour available in which to take the test.

If possible ask someone to drive you home, since after fasting and drinking the liquid, you may feel light headed.

What complications can the test cause?

Some women will experience some minor problems from the test including:

For this reason it's important to stay at the testing centre during the entire testing period.





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Monday, 1 July 2013

Gestational Diabetes Test - What is it And How do I Prepare?

During even a low risk pregnancy, you'll find there are many different tests you'll experience, from the first pregnancy test through to regular urine tests, blood pressure tests, blood tests and a gestational diabetes test.

Gestational diabetes is a complication more common in women who have health or weight problems or are experiencing pregnancy at an older age. Even if you're not in the risk category for gestational diabetes you'll still probably be tested for it.

Before you begin to worry about such a scary sounding problem, just remember this - many women who get it have never had any type of diabetes before pregnancy and many of these women often find it disappears within a few weeks of baby's birth. The most important thing is diagnosing and treating it during pregnancy.

This article is written as a guide to Glucose Tolerance Tests, what to expect and how to prepare for them.

What is Gestational Diabetes?

Gestational Diabetes is a pregnancy induced problem with the insulin produced by your pancreas. The insulin plays in important role in processing the sugars you eat.

What are the risks of having untreated Gestational Diabetes?

Some of the basic problems associated with Gestational Diabetes include very large babies, which may lead to an early induction or caesarian.

The large amount of glucose that crosses through the placenta forces the baby's pancreas to work overtime. Baby's body will create extra energy which is then stored as fat. This can also lead to higher risk of obesity and diabetes in later life for the child.

Glucose problems can also have an adverse effect on baby's breathing at birth.

What does the Glucose drink taste and look like?

The Glucose drink doesn't taste bad - in fact it tastes almost exactly like lemonade. It's a clear liquid in a small bottle and is generally only about 500 ml.

What types of Glucose Tolerance Tests are there?

There are several types of tests, depending on where you live and your risk of having gestational diabetes.

The tests are known as Glucose Tolerance Tests (GTT) and involve drinking a sugary liquid after which you'll be tested to see how your body reacts to the liquid.

Preparing for your Test

It's important to prepare for the test correctly, so that you don't have a false positive or need to retake the test. The following are guidelines only and should be checked with your doctor before the test.

Don't eat or drink anything but water in the 12 hours before the test. (If you do, it may result in a false positive.)

Make sure you have at least an hour available in which to take the test.

If possible ask someone to drive you home, since after fasting and drinking the liquid, you may feel light headed.

What complications can the test cause?

Some women will experience some minor problems from the test including:

For this reason it's important to stay at the testing centre during the entire testing period.





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Early symptoms of diabetes: Saves the Intensity

It was very wisely said by William Shakespeare, 'Sweets are the uses of adversity'. It is common belief that a person consuming too much pf sweet gets affected with diabetics. And to be precise, it can even affect individuals who are quite healthy. When people come across diabetes, they get panic and somehow start feeling sick. One thing is very clear; proper diagnosis, strict diet, regular exercise, and medicine/insulin are the best way to live healthy diabetic life.

Well, no doubt that the management of diabetes has been advanced in modern world. It is very necessary to get proper diagnosis. Certain symptoms can in fact warn us about diabetes. But for that we should have proper information in regards with symptoms. Seriously, there is no need to get worried about diabetic life or diagnosis. The step towards early diagnosis can overcome the intensity of this ailment.

Diabetes is a state where normally, an individual possess high level of sugar in blood. Or even when the body is incapable of generating sufficient amount of insulin for normal functioning of organs is associated with diabetes. Sometimes in this state, body does not respond properly to the insulin created in pancreas. Thus, when body does not absorb the glucose, it leads to hyperglycemia.

It is necessary to understand the proper early symptoms of diabetes, to act accordingly. The standard symptoms of diabetes are rapid loss of weight, excessive thirst, frequent urination, and extreme hunger. But, if these symptoms are developing gradually, and are not very severe, then they cannot be alarming sign. Moreover, in mild and moderate cases, the symptoms might not even exist. This is the main reason for diabetes to be remained undetected for so long period. Usually, a blood or urine test detects diabetes. Sometimes, diabetes is first diagnosed when the patient has repetitive infections. An ulcer which refuses to heal, continuous itching or rashes over skin are also the symptoms of diabetes.

Other symptoms like retinopathy- abnormality in retina, nephropathy- abnormalities in kidneys, and neuropathy- abnormality of nerves informs us about diabetes. This forecast can be made available to people technically, having impaired glucose tolerance, or IGT on the basis of blood test. If the diabetic person understands his won problem and participates actively in his own treatment, he may live more productive and healthy life.

Donna Brown is a health researcher in health and fitness. She writes about nutritious food, dental care to fit healthy. Get more information about Cardiovascular system, cardiovascular exercises and Early symptoms of diabetes on





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